Lateral Flow Strip (for CRISPR SHERLOCK)

This product is based on the lateral flow technology using gold nanoparticles. It is able to give information about the status of reporter, a short single stranded DNA- or RNA-molecule with dual-label of Biotin & FAM or Biotin &FITC.
Successful target recognition of the CRISPR/Cas complex triggers collateral nuclease activity of the Cas Protein. Cas-dependent reporter cleavage leads to the separate of the FAM/FITC and Biotin labels. The paper strip is able to differentiate between intact and cleaved reporter. Recommend to use with CRISPR-Cas12a DNA detection kit